Article
Bone marrow stromal cells as targets for gene therapy.
Current gene therapy - 1 May 2002
Van Damme An, Vanden Driessche Thierry, Collen Desire, Chuah Marinee K L
Abstract excerpt
The bone marrow (BM) is composed of the non-adherent hematopoietic and adherent stromal cell compartment. This adherent BM stromal cell fraction contains pluripotent mesenchymal stem cells (MSCs) and differentiated mesenchymal BM stromal cells. The MSCs self-renew by proliferation while maintaining their stem-cell phenotype and give rise to the differentiated stromal cells which belong to the osteogenic,...
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