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Article

The influence of hypoxia on the differentiation capacities and immunosuppressive properties of clonal mouse mesenchymal stromal cell lines.

Immunology and cell biology - 1 Aug 2014

Prado-Lòpez Sonia, Duffy Michelle M, Baustian Claas, Alagesan Senthilkumar, Hanley Shirley A, Stocca Alessia, Griffin Matthew D, Ceredig Rhodri

Abstract excerpt

Multipotent mesenchymal stromal cells are multipotent cells capable of differentiating into different mesodermal cell types. Enigmatically, mesenchymal stromal cells present in the bone marrow support early lymphopoiesis yet can inhibit mature lymphocyte growth. Critical features of the bone marrow microenvironment, such as the level of oxygen, play an important role in mesenchymal stromal cell biology. Herein,...

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PMID: 24777310
DOI: 10.1038/icb.2014.30

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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