Article
Localization of a PlA1 epitope to the amino terminal 66 residues of platelet glycoprotein IIIa.
Blood - 1 Feb 1992
Bowditch R D, Tani P H, Halloran C E, Frelinger A L, McMillan R, Ginsberg M H
Abstract excerpt
A platelet glycoprotein (GP) IIIa epitope library was constructed by insertion of randomly cleaved GPIIIa cDNA fragments in the prokaryotic expression vector lambda gt22 and screened with purified anti-PlA1 antibodies for clones expressing a PlA1 epitope. Five independent clones were isolated and characterized by nucleotide sequencing. The smallest anti-PlA1 reactive clone obtained encoded the amino terminal 66...
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