Article
Localization of a PlA1 epitope to the amino terminal 66 residues of platelet glycoprotein IIIa.
Blood - 1 Feb 1992
Bowditch R D, Tani P H, Halloran C E, Frelinger A L, McMillan R, Ginsberg M H
Abstract excerpt
A platelet glycoprotein (GP) IIIa epitope library was constructed by insertion of randomly cleaved GPIIIa cDNA fragments in the prokaryotic expression vector lambda gt22 and screened with purified anti-PlA1 antibodies for clones expressing a PlA1 epitope. Five independent clones were isolated and...
Topics
- Alleles
- Amino Acid Sequence
- DNA Mutational Analysis
- Epitopes
- Humans
- Molecular Sequence Data
- Phenotype
- Platelet Membrane Glycoproteins
- Recombinant Proteins