Article
Identification and Regulation of TCRαβ+CD8αα+ Intraepithelial Lymphocytes in Murine Oral Mucosa.
Frontiers in immunology - 1 Jan 2020
Wu Ruiqing, Zhang Dunfang, Zanvit Peter, Jin Wenwen, Wang Hao, Chen WanJun
Abstract excerpt
TCRαβ+CD8αα+ intraepithelial lymphocytes (IELs) are abundant in gastrointestinal (GI) tract and play an important role in regulation of mucosal immunity and tolerance in the gut. However, it is unknown whether TCRαβ+CD8αα+ IELs exist in the oral mucosa and if yes, what controls their development. We here identified and characterized TCRαβ+CD8αα+ IELs from the murine oral mucosa. We showed that the number and...
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