Article
Age-associated changes in rat immune system: lessons learned from experimental autoimmune encephalomyelitis.
Experimental gerontology - 1 Oct 2014
Djikić Jasmina, Nacka-Aleksić Mirjana, Pilipović Ivan, Stojić-Vukanić Zorica, Bufan Biljana, Kosec Duško, Dimitrijević Mirjana, Leposavić Gordana
Abstract excerpt
Aging is associated with the decline in immune response to infectious agents and tumors and increasing risk of autoimmunity, but the incidence of autoimmune diseases does not increase in the elderly. To elucidate the cellular and molecular mechanisms influencing clinical expression of autoimmunity in aged animals, the phenotypic and functional characteristics of mononuclear cells isolated from the spinal cords of...
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