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Article

Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy.

Human molecular genetics - 15 Sept 2007

Van Limbergen Johan, Nimmo Elaine R, Russell Richard K, Drummond Hazel E, Smith Linda, Anderson Niall H, Davies Gail, Arnott Ian D, Wilson David C, Satsangi Jack

Abstract excerpt

Both NOD1/CARD4 and NOD2/CARD15 are intracellular pattern-recognition receptors involved in the innate immune response. Germline NOD2/CARD15 variation has a definite effect on susceptibility to Crohn's disease (CD) and phenotype, although this contribution is weak in Scotland and Scandinavia. The NOD1/CARD4 gene lies within the putative inflammatory bowel disease (IBD) locus at 7p14.3. We have assessed, in...

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Source

Identifiers

PMID: 17613538
DOI: 10.1093/hmg/ddm169

Genes

NOD1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy.PMID 17613538Read ↗

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