Article
Expression profiles of pancreatic cancer cell lines infected with antisense K-ras-expressing adenoviral vector.
Biochemical and biophysical research communications - 3 Oct 2003
Ohnami Shumpei, Aoki Kazunori, Yoshida Kimiko, Ohnami Sumiko, Hatanaka Kazuteru, Suzuki Koichi, Sasaki Hiroki, Yoshida Teruhiko
Abstract excerpt
The point mutations of the K-ras gene occur in as high as 70-90% of the cases with adenocarcinoma of the pancreas and apparently represent one of the key and early events in the carcinogenesis. However, the specific influence of the K-ras activation on global gene expression profiles in pancreati...
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