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Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.

Oncogene - 20 Jan 2005

Lebedeva Irina V, Su Zao-Zhong, Sarkar Devanand, Gopalkrishnan Rahul V, Waxman Samuel, Yacoub Adly, Dent Paul, Fisher Paul B

Abstract excerpt

Pancreatic cancer is exceptionally aggressive with no long-term effective therapy. Current interventional approaches, including surgery, radiation and/or chemotherapy, have done little to quell the mortality associated with this malignancy. Subtraction hybridization identified a cancer-specific a...

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PMID: 15580305
DOI: 10.1038/sj.onc.1208183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15580305-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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