Article
Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants.
FEBS letters - 24 Mar 2000
DeRisi J, van den Hazel B, Marc P, Balzi E, Brown P, Jacq C, Goffeau A
Abstract excerpt
The cDNA from activated mutants of the homologous transcription factors Pdr1p and Pdr3p was used to screen DNA microarrays of the Saccharomyces cerevisiae complete genome. Twenty-six overexpressed targets of the PDR1-3 and/or PDR3-7 mutants were identified. Twenty-one are new targets, the majority of which are of unknown function. In addition to well known ABC transporters, these targets appear to be involved in...
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