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Article

Yeast ABC proteins involved in multidrug resistance

2 Dec 2013

Abstract excerpt

Pleiotropic drug resistance is a complex phenomenon that involves many proteins that together create a network. One of the common mechanisms of multidrug resistance in eukaryotic cells is the active efflux of a broad range of xenobiotics through ATP-binding cassette (ABC) transporters. Saccharomyces cerevisiae is often used as a model to study such activity because of the functional and structural similarities of...

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PMID: 24297686
DOI: 10.2478/s11658-013-0111-2

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