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Article

Requirement of the paraxis gene for somite formation and musculoskeletal patterning.

Nature - 12 Dec 1996

Burgess R, Rawls A, Brown D, Bradley A, Olson E N

Abstract excerpt

The segmental organization of the vertebrate embryo is first apparent when somites form in a rostrocaudal progression from the paraxial mesoderm adjacent to the neural tube. Newly formed somites appear as paired epithelial spheres that become patterned to form vertebrae, ribs, skeletal muscle and...

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Identifiers

PMID: 8955271
DOI: 10.1038/384570a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8955271-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement of the paraxis gene for somite formation and musculoskeletal patterning.PMID 8955271Read ↗

Differential regulation of epaxial and hypaxial muscle development by paraxis.Semantic proximity Read ↗

The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites.Semantic proximity Read ↗

Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis.Semantic proximity Read ↗

Reconstituting human somitogenesis <i>in vitro</i>Semantic proximity Read ↗

The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.Semantic proximity Read ↗

Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation.Semantic proximity Read ↗

Understanding paraxial mesoderm development and sclerotome specification for skeletal repairSemantic proximity Read ↗

Somite development in zebrafish.Semantic proximity Read ↗

Reconstituting human somitogenesis in vitro.Semantic proximity Read ↗

Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints.Semantic proximity Read ↗

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm <i>in vitro</i>Semantic proximity Read ↗

Paraxial mesoderm organoids model development of human somitesSemantic proximity Read ↗

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