DNA synthesis control in yeast: an evolutionarily conserved mechanism for regulating DNA synthesis genes?

doi:10.1002/bies.950141206

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Article

DNA synthesis control in yeast: an evolutionarily conserved mechanism for regulating DNA synthesis genes?

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 1992

Merrill G F, Morgan B A, Lowndes N F, Johnston L H

Abstract excerpt

After yeast cells commit to the cell cycle in a process called START, genes required for DNA synthesis are expressed in late G1. Periodicity is mediated by a hexameric sequence, known as a MCB element, present in all DNA synthesis gene promoters. A complex that specifically binds MCBs has been identified. One polypeptide in the MCB complex is Swi6, a transcription factor that together with Swi4 also binds G1...

Topics

Animals
Base Sequence
Cell Cycle
DNA Replication
DNA, Fungal
Feedback
Fungal Proteins
Genes, Fungal
Models, Genetic
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Replication Origin

Saccharomyces cerevisiae

Sequence Alignment

Sequence Homology, Nucleic Acid

Transcription Factors

Vertebrates

Source

Open in PubMed

Identifiers

PMID: 1365898
DOI: 10.1002/bies.950141206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1365898-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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