Article
DNA synthesis control in yeast: an evolutionarily conserved mechanism for regulating DNA synthesis genes?
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 1992
Merrill G F, Morgan B A, Lowndes N F, Johnston L H
Abstract excerpt
After yeast cells commit to the cell cycle in a process called START, genes required for DNA synthesis are expressed in late G1. Periodicity is mediated by a hexameric sequence, known as a MCB element, present in all DNA synthesis gene promoters. A complex that specifically binds MCBs has been identified. One polypeptide in the MCB complex is Swi6, a transcription factor that together with Swi4 also binds G1...
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