Differentiation of the U-937 promonocytic cell line induced by phorbol myristate acetate or retinoic acid: effect of aurothiomalate.

doi:10.1007/BF02028124

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Article

Differentiation of the U-937 promonocytic cell line induced by phorbol myristate acetate or retinoic acid: effect of aurothiomalate.

Agents and actions - 1 Nov 1992

Joyce D A, Steer J H

Abstract excerpt

Tissue macrophages, which participate in chronic synovial inflammation, differentiate from haemopoietic precursors in bone marrow and subsequently in tissue. During this process, they acquire attributes which are essential for their function in inflammation. Modulation of this process may represe...

Topics

Cell Differentiation
Cell Line
Gold Sodium Thiomalate
Humans
Monocytes
N-Formylmethionine Leucyl-Phenylalanine
Oxygen Consumption
Phenotype
Superoxides
Tetradecanoylphorbol Acetate
Thymidine
Tretinoin
gamma-Glutamyltransferase

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