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Article

Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis.

The Journal of biological chemistry - 7 Sept 2001

Antonyak M A, Singh U S, Lee D A, Boehm J E, Combs C, Zgola M M, Page R L, Cerione R A

Abstract excerpt

Retinoic acid (RA) and its various synthetic analogs affect mammalian cell growth, differentiation, and apoptosis. Whereas treatment of the human leukemia cell line HL60 with RA results in cellular differentiation, addition of the synthetic retinoid, N-(4-hydroxyphenyl) retinamide (HPR), induces HL60 cells to undergo apoptosis. Moreover, pretreatment of HL60 cells as well as other cell lines (i.e. NIH3T3 cells)...

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Source

Identifiers

PMID: 11438548
DOI: 10.1074/jbc.M105318200

Genes

HPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis.PMID 11438548Read ↗

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