Article
Resistance of HIV-1 to AZT might also involve the cellular expression of multidrug resistance P-glycoprotein.
AIDS research and human retroviruses - 1 Oct 1992
Antonelli G, Turriziani O, Cianfriglia M, Riva E, Dong G, Fattorossi A, Dianzani F
Abstract excerpt
Resistance of tumor cells to the antigrowth activity of several cytotoxic compounds has been associated with the expression of the so-called multidrug resistance protein or P-glycoprotein. This article addresses the question whether the expression of such protein could also affect the sensitivity...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Cell Division
- Cell Line
- Drug Resistance, Microbial
- Gene Expression
- HIV-1
- Humans
- Membrane Glycoproteins
- Phenotype
- Trifluoperazine
- Vinblastine