Article
An immunogenetic heterogeneity in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry - 1 Oct 1992
Hillert J, Grönning M, Nyland H, Link H, Olerup O
Abstract excerpt
Two clinical forms of multiple sclerosis (MS), primarily chronic progressive MS (PCP MS) and relapsing/remitting MS (R/R MS) have been shown to differ in several respects. The results of genomic HLA class II typing with restriction fragment length polymorphism analysis of 62 MS patients from Western Norway, 42 with R/R MS and 20 PCP MS, are reported on here. As in previous studies of Swedish patients, the...
Topics
- Adult
- DNA Probes
- Female
- Follow-Up Studies
- Gene Frequency
- Genetic Testing
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Male
- Multiple Sclerosis
