T-cell receptor variable genes and genetic susceptibility to celiac disease: an association and linkage study.

doi:10.1016/0016-5085(93)91077-u

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Article

T-cell receptor variable genes and genetic susceptibility to celiac disease: an association and linkage study.

Gastroenterology - 1 Dec 1993

Roschmann E, Wienker T F, Gerok W, Volk B A

Abstract excerpt

BACKGROUND: Genetic susceptibility of celiac disease is primarily associated with a particular combination of and HLA-DQA1/DQB1 gene; however, this does not fully account for the genetic predisposition. Therefore, the aim of this study was to examine whether T-cell receptor (TCR) genes may be sus...

Topics

Adolescent
Adult
Aged
Base Sequence
Celiac Disease
Child
Child, Preschool
Female
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR3 Antigen
Humans
Male
Middle Aged
Molecular Sequence Data

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