Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A single-base-pair substitution abolishes D-amino-acid oxidase activity in the mouse.

Biochimica et biophysica acta - 25 Aug 1992

Sasaki M, Konno R, Nishio M, Niwa A, Yasumura Y, Enami J

Abstract excerpt

Mutant ddY/DAO- mice lacking D-amino-acid oxidase (DAO) activity were examined for the cause of their lack of enzyme activity. Total RNA was extracted from the kidney of the ddY/DAO- mice and cDNA was synthesized. After cDNA encoding DAO was amplified by the polymerase chain reaction it was cloned into a plasmid and sequenced. Comparison of the DAO cDNA sequence with that of normal BALB/c mice revealed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Composition
Share to Base Sequence
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoblotting

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 1355365
DOI: 10.1016/0925-4439(92)90107-x

Genes

DAO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

A single-base-pair substitution abolishes D-amino-acid oxidase activity in the mouse.PMID 1355365Read ↗

d-Amino acid oxidase deficiency is caused by a large deletion in the Dao gene in LEA rats.Semantic proximity Read ↗

Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis.Semantic proximity Read ↗

The murine mutation jaundiced is caused by replacement of an arginine with a stop codon in the mRNA encoding the ninth repeat of beta-spectrin.Semantic proximity Read ↗

Retinal NMDA receptor function and expression are altered in a mouse lacking D-amino acid oxidase.Semantic proximity Read ↗

A missense mutation of L-gulono-gamma-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid.Semantic proximity Read ↗

Null allele at Bcd-1 locus in BALB/cByJ mice is due to a deletion in the short-chain acyl-CoA dehydrogenase gene and results in missplicing of mRNA.Semantic proximity Read ↗

Ddx1 knockout results in transgenerational wild-type lethality in mice.Semantic proximity Read ↗

Molecular basis of dark-eyed albinism in the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.