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Article

Null allele at Bcd-1 locus in BALB/cByJ mice is due to a deletion in the short-chain acyl-CoA dehydrogenase gene and results in missplicing of mRNA.

Genomics - 1 Jun 1993

Hinsdale M E, Kelly C L, Wood P A

Abstract excerpt

BALB/cByJ mice have a deficiency of short-chain acyl-CoA dehydrogenase (SCAD), an enzyme of fatty acid beta-oxidation. This mutant mouse strain represents the only animal model for any human inborn error of fatty acid metabolism. We have investigated the molecular basis of this defect by DNA and...

Topics

Acyl-CoA Dehydrogenase
Acyl-CoA Dehydrogenases
Alleles
Animals
Base Sequence
Blotting, Northern
Blotting, Southern
DNA
Genes
Humans
Mice
Mice, Inbred BALB C
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

RNA Splicing

RNA, Messenger

Sequence Deletion

Source

Identifiers

PMID: 8325633
DOI: 10.1006/geno.1993.1237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8325633-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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