Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule.

Nature - 21 May 1992

Powis S J, Deverson E V, Coadwell W J, Ciruela A, Huskisson N S, Smith H, Butcher G W, Howard J C

Abstract excerpt

Short antigenic peptides bound in the groove of class I major histocompatibility complex molecules enable T cells to detect intracellular pathogens. It has been assumed that structural features of the class I molecule alone select which peptides are bound. It is now demonstrated that a complex polymorphism in one of the major histocompatibility complex-encoded putative peptide-transporter genes is associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinetics

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 1350326
DOI: 10.1038/357211a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule.PMID 1350326Read ↗

Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function.Semantic proximity Read ↗

Sequence variability analysis of human class I and class II MHC molecules: functional and structural correlates of amino acid polymorphisms.Semantic proximity Read ↗

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules.Semantic proximity Read ↗

Analysis of the structure of naturally processed peptides bound by class I and class II major histocompatibility complex molecules.Semantic proximity Read ↗

Sequence-structure-function relationships in class I MHC: a local frustration perspectiveSemantic proximity Read ↗

Modeling alternative binding registers of a minimal immunogenic peptide on two class II major histocompatibility complex (MHC II) molecules predicts polarized T-cell receptor (TCR) contact positions.Semantic proximity Read ↗

Computational characterization of residue couplings and micropolymorphism-induced changes in the dynamics of two differentially disease-associated human MHC class-I alleles.Semantic proximity Read ↗

Ancestral polymorphisms of MHC class II genes: divergent allele advantage.Semantic proximity Read ↗

Complete nucleotide sequence of MHC class I alleles in the HT29 colon cancer cell line.Semantic proximity Read ↗

Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing.Semantic proximity Read ↗

Allelic variation alters expression and antigen presentation of MR1 allomorphs.Semantic proximity Read ↗

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. 1991.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.