An approach to the localization of the susceptibility genes for generalized myasthenia gravis by mapping recombinant ancestral haplotypes.

doi:10.1007/BF00179791

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Article

An approach to the localization of the susceptibility genes for generalized myasthenia gravis by mapping recombinant ancestral haplotypes.

Immunogenetics - 1 Jan 1992

Degli-Esposti M A, Andreas A, Christiansen F T, Schalke B, Albert E, Dawkins R L

Abstract excerpt

The association of HLA A1, B8, and DR3 with generalized myasthenia gravis (GMG) in Caucasoids is well established, but no particular gene has been implicated and there is still no adequate explanation in functional terms. In this study we have taken advantage of sequential genomic markers between...

Topics

Blotting, Southern
Chromosome Mapping
Complement C4
Female
Gene Frequency
Genetic Markers
Genetic Predisposition to Disease
HLA-A1 Antigen
HLA-B8 Antigen
HLA-DR3 Antigen
Haplotypes
Humans
Immunophenotyping
Myasthenia Gravis
Polymorphism, Restriction Fragment Length
Tumor Necrosis Factor-alpha
White People

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Open in PubMed

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PMID: 1349584
DOI: 10.1007/BF00179791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1349584-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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