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Article

Novel genetic loci associated HLA-B*08:01 positive myasthenia gravis.

Journal of autoimmunity - 1 Mar 2018

Varade Jezabel, Wang Ning, Lim Che Kang, Zhang Tao, Zhang Yuanwei, Liu Xiaomin, Piehl Fredrik, Matell Ritva, Cao Hongzhi, Xu Xun, Hammarström Lennart

Abstract excerpt

OBJECTIVE: To identify potential causative markers involved in the development of early-onset myasthenia gravis (EOMG) in the MHC and non-MHC regions that may interact with the HLA-B*08:01 allele. METHODS: We analyzed 583 MG patients and identified 5 patients homozygous for the disease-associated ancestral haplotype 8.1 (HLA-A*01:01, B*08:01, DRB1*03:01, DQB1*02:01). We also analyzed more than 9000 controls and...

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Source

Identifiers

PMID: 29037440
DOI: 10.1016/j.jaut.2017.10.002

Genes

OVCH1
CNPY2
ZBTB9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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