Article
Characterization of six rat strains (Rattus norvegicus) by mitochondrial DNA restriction fragment length polymorphism.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Mar 1999
Hilsdorf A W, Krieger J E
Abstract excerpt
Restriction fragment length polymorphism (RFLP) was used to examine the extent of mtDNA polymorphism among six strains of rats (Rattus norvegicus)--Wistar, Wistar Munich, Brown Norway, Wistar Kyoto, SHR and SHR-SP. A survey of 26 restriction enzymes has revealed a low level of genetic divergence among strains. The sites of cleavage by EcoRI, NcoI and XmnI were shown to be polymorphic. The use of these three...
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