Article
Allelic loss at chromosome 3p characterizes clear cell phenotype of renal cell carcinoma.
Cancer research - 1 Feb 1991
Ogawa O, Kakehi Y, Ogawa K, Koshiba M, Sugiyama T, Yoshida O
Abstract excerpt
Incidence of the loss of heterozygosity on chromosome 3p was evaluated using 7 polymorphic probes in 35 Japanese patients with sporadic renal cell carcinoma (RCC). Overall frequency of the loss of heterozygosity on 3p was 53%, representing 16 of 30 informative cases. Examination of the relationship between histopathological phenotypes of RCC and incidence of the 3p loss revealed that the loss of heterozygosity in...
Topics
- Carcinoma, Renal Cell
- Chromosome Deletion
- Chromosomes, Human, Pair 3
- Heterozygote
- Humans
- Japan
- Kidney Neoplasms
- Phenotype
- Polymorphism, Restriction Fragment Length
