Article
Chromosome 3 imbalances are the most frequent aberration found in non-small cell lung carcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 1999
Lu Y J, Dong X Y, Shipley J, Zhang R G, Cheng S J
Abstract excerpt
The chromosomal imbalances in nine cases of primary non-small cell lung cancer (NSCLC) and two cell lines derived from normal human bronchial epithelial (HBE) tissue were identified by comparative genomic hybridization (CGH). Gain of material from 3q and loss of 3p material were the most frequent changes in the primary tumors. Other commonly found imbalances included gain of material from 1q, 7p, 8q, 9q, 17q and...
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