Article
Impairment of MHC class I transcription in a mutant bovine B cell line.
Immunogenetics - 1 Jan 1992
Harms J S, Splitter G A
Abstract excerpt
To better define the regulation and expression of bovine major histocompatibility complex (MHC) antigens, the bovine B lymphoblastoid cell line, BL3, was exposed to gamma-irradiation and surviving cells were immunoselected for MHC class I antigen loss. The resulting class I expression loss variant, BL3.1, was characterized at both the protein and genetic levels to ascertain the nature of the defect....
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