Article
Negative regulation of mitosis by the fission yeast protein phosphatase ppa2.
Genes & development - 1 Jun 1993
Kinoshita N, Yamano H, Niwa H, Yoshida T, Yanagida M
Abstract excerpt
To understand the role of the type 2A-like protein phosphatase in the cell division cycle, we investigated the mutant phenotypes obtained when the fission yeast ppa1+ and ppa2+ phosphatase genes (which encode polypeptides with approximately 80% identity to mammalian type 2A phosphatases) were either deleted or overexpressed. We also investigated the in vivo effect of okadaic acid, an inhibitor of protein...
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