Article
Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Dec 2011
Yanagida Mitsuhiro, Ikai Nobuyasu, Shimanuki Mizuki, Sajiki Kenichi
Abstract excerpt
In dividing fission yeast Schizosaccharomyces pombe cells, the balance between Wee1 kinase and Cdc25 phosphatase which control the cyclin-dependent kinase (CDK) at the G2-M transition determines the rod-shaped cell length. Under nitrogen source starvation or glucose limitation, however, cell size determination is considerably modulated, and cell size shortening occurs for wild-type cells. For several mutants of...
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