Article
Comparison of the biochemical and biological functions of tyrosine phosphatases from fission yeast, budding yeast and animal cells.
Yeast (Chichester, England) - 1 Oct 1993
Hannig G, Ottilie S, Schievella A R, Erikson R L
Abstract excerpt
In a previous communication, we have shown that two protein tyrosine tyrosine phosphatases (PTPases) from fission yeast, pyp1+ and pyp2+, act as novel inhibitors of mitosis upstream of the wee1+/mik1+ pathway (Ottilie et al., 1992). Here we describe that both genes possess intrinsic PTPase activity as judged by in vitro PTPase assays using 32P-labeled Raytide as a substrate, and that 32P-labeled p107wee1 is an in...
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