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Article

Proteolysis in MHC class II antigen presentation: who's in charge?

Immunity - 1 Mar 2000

Villadangos J A, Ploegh H L

Abstract excerpt

Antigen-presenting cells (APC) degrade proteins intracellularly to generate peptides, which are then bound by products of the major histocompatibility complex (MHC) and exposed on the surface of the APC for recognition by T cells. The supply of antigenic peptides and their association with MHC molecules requires the concerted action of a cohort of accessory molecules that includes chaperones, transporters of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10755610
DOI: 10.1016/s1074-7613(00)80176-4

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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