Article
Arylamine N-acetyltransferase in human red blood cells.
Biochemical pharmacology - 25 Sept 1992
Ward A, Hickman D, Gordon J W, Sim E
Abstract excerpt
N-Acetyltransferase activities associated with erythrocytes from 20 individuals have been determined with p-aminobenzoic acid as substrate. A three-fold variation in Vmax is found. The N-acetyltransferase genotype of the individuals has been determined and there is no correlation between the extent of acetylation measured in the individuals' erythrocytes and the inheritance of alleles at the polymorphic NAT...
Topics
- 4-Aminobenzoic Acid
- Arylamine N-Acetyltransferase
- Base Sequence
- DNA Restriction Enzymes
- Erythrocytes
- Folic Acid
- Gene Amplification
- Genotype
- Humans
- Kinetics
- Methotrexate
- Molecular Sequence Data
