Screening for alpha-thalassemia. Correlation of hemoglobin H inclusion bodies with DNA-determined genotype.

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Article

Screening for alpha-thalassemia. Correlation of hemoglobin H inclusion bodies with DNA-determined genotype.

Archives of pathology & laboratory medicine - 1 Oct 1992

Skogerboe K J, West S F, Smith C, Terashita S T, LeCrone C N, Detter J C, Tait J F

Abstract excerpt

We evaluated potential screening protocols for alpha-thalassemia in a group of 80 patients whose genotypes were determined by Southern blot analysis with alpha- and zeta-globin DNA probes. Erythrocyte inclusion bodies were measured by a modified brilliant cresyl blue test. Erythrocyte indices and...

Topics

Blotting, Southern
Coloring Agents
DNA
Erythrocyte Indices
Ferritins
Genotype
Globins
Hemoglobin H
Humans
Inclusion Bodies
Mass Screening
Oxazines
alpha-Thalassemia

Source

Open in PubMed

Identifiers

PMID: 1329692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1329692-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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