Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of a single-tube multiplex polymerase chain reaction screen for detection of common alpha-thalassemia genotypes in a clinical laboratory.

American journal of clinical pathology - 1 Jul 2002

Bergstrome Jones Alana K, Poon Annette

Abstract excerpt

We prospectively compared a single-tube multiplex polymerase chain reaction (PCR) for detecting alpha-thalassemia with our current approach using 452 blood samples. Initial evaluation of 89 specimens revealed sensitivity and specificity, respectively, for the hemoglobin H inclusion body test (HbH prep) vs PCR for detecting alpha0-thalassemia carriers of 0.79 and 0.96 and for a mean corpuscular volume (MCV) of 82...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Thalassemia
Share to DNA
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Erythrocyte Indices

Share to Hemoglobin H

Share to Mass Screening

Share to Polymerase Chain Reaction

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 12109851
DOI: 10.1309/3VK2-UCJ1-5GBJ-QV8Q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of a single-tube multiplex polymerase chain reaction screen for detection of common alpha-thalassemia genotypes in a clinical laboratory.PMID 12109851Read ↗

Single-tube multiplex-PCR screen for common deletional determinants of α-thalassemiaSemantic proximity Read ↗

Molecular Detection of alpha Thalassemia: A Review of Prevalent TechniquesSemantic proximity Read ↗

Screening for alpha-thalassemia. Correlation of hemoglobin H inclusion bodies with DNA-determined genotype.Semantic proximity Read ↗

Sensitivity and specificity of mean corpuscular volume testing for screening for α‐thalassemia‐1 and β‐thalassemia traitsSemantic proximity Read ↗

Detection of Severe Nondeletional α -Thalassemia Mutations Using a Single-Tube Multiplex ARMS AssaySemantic proximity Read ↗

Alpha-thalassemia carrier identification by DNA analysis in the screening for thalassemia.Semantic proximity Read ↗

Cut-off Values of Hematologic Parameters to Predict the Number of Alpha Genes Deleted in Subjects with Deletional Alpha ThalassemiaSemantic proximity Read ↗

Improvement of alpha(0)-thalassemia screening using combined osmotic fragility, dichlorophenolindophenol and Hb H inclusion tests.Semantic proximity Read ↗

Simplified multiplex-PCR diagnosis of common southeast asian deletional determinants of alpha-thalassemia.Semantic proximity Read ↗

A rapid and reliable 7-deletion multiplex polymerase chain reaction assay for α-thalassemiaSemantic proximity Read ↗

Rapid differentiation of five common alpha-thalassemia genotypes by polymerase chain reaction.Semantic proximity Read ↗

Feasibility of molecular diagnosis of alpha-thalassemia in the evaluation of microcytosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.