Article
Alpha-thalassemia carrier identification by DNA analysis in the screening for thalassemia.
American journal of hematology - 1 Dec 1998
Galanello R, Sollaino C, Paglietti E, Barella S, Perra C, Doneddu I, Pirroni M G, Maccioni L, Cao A
Abstract excerpt
Differentiation between heterozygous alpha-thalassemia and several phenotypically resembling alleles at the beta-globin gene cluster such as coinherited delta- and beta-thalassemia or gammadelta beta-thalassemia is a critical step in genetic counseling. In this paper we report our experience in t...
Topics
- Adult
- Alleles
- DNA Mutational Analysis
- Erythrocyte Indices
- Feasibility Studies
- Female
- Genetic Carrier Screening
- Genetic Testing
- Genotype
- Globins
- Hematocrit
- Humans