Article
Alpha-thalassemia carrier identification by DNA analysis in the screening for thalassemia.
American journal of hematology - 1 Dec 1998
Galanello R, Sollaino C, Paglietti E, Barella S, Perra C, Doneddu I, Pirroni M G, Maccioni L, Cao A
Abstract excerpt
Differentiation between heterozygous alpha-thalassemia and several phenotypically resembling alleles at the beta-globin gene cluster such as coinherited delta- and beta-thalassemia or gammadelta beta-thalassemia is a critical step in genetic counseling. In this paper we report our experience in the identification of the alpha-thalassemia carrier state using polymerase chain reaction (PCR)-based methods, and the...
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