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Article

The simultaneous presence of alpha- and beta-thalassaemia alleles: a pitfall of thalassaemia screening.

Community genetics - 1 Jan 2003

Law H Y, Chee M K L, Tan G P, Ng I S L

Abstract excerpt

OBJECTIVE: To compare the efficacy of routine haematological tests and molecular analysis in the diagnosis of double heterozygous alpha- and beta-thalassaemia. METHODS: Screening was carried out in extended family members from 125 families registered in the National Thalassaemia Registry, known to have both alpha- and beta-thalassaemia carriers. RESULTS: Eighty-three individuals from 59 families were identified...

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PMID: 12748434
DOI: 10.1159/000069539

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