Article
Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication.
Journal of virology - 1 Jul 1996
Ferguson M K, Botchan M R
Abstract excerpt
The bovine papillomavirus protein E2 serves dual functions in viral transcription and in the initiation of viral replication. As a transcription factor, E2 can cooperatively interact with cellular proteins such as SP1 and stimulate transcription of distal promoters. In replication, E2 and the hel...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Bovine papillomavirus 1
- Cattle
- Cell Line
- Chlorocebus aethiops
- DNA-Binding Proteins
- Genetic Vectors
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Structure-Activity Relationship
- Temperature
- Transcription, Genetic
- Viral Proteins
- Virus Replication