Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication.

Journal of virology - 1 Jul 1996

Ferguson M K, Botchan M R

Abstract excerpt

The bovine papillomavirus protein E2 serves dual functions in viral transcription and in the initiation of viral replication. As a transcription factor, E2 can cooperatively interact with cellular proteins such as SP1 and stimulate transcription of distal promoters. In replication, E2 and the helicase El are the only viral proteins required for accurate replication of templates containing the viral origin. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Binding Sites
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Molecular Sequence Data

Share to Mutagenesis

Share to Phenotype

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8676438
DOI: 10.1128/JVI.70.7.4193-4199.1996
PMCID: PMC190348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication.PMID 8676438Read ↗

Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication Functions.Semantic proximity Read ↗

A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention.Semantic proximity Read ↗

The bovine papillomavirus E2 transactivator is stimulated by the E1 initiator through the E2 activation domain.Semantic proximity Read ↗

Mutations in the human papillomavirus type 16 E2 protein identify multiple regions of the protein involved in binding to E1.Semantic proximity Read ↗

Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA ProcessingSemantic proximity Read ↗

Functional analysis of a carboxyl-terminal phosphorylation mutant of the bovine papillomavirus E1 protein.Semantic proximity Read ↗

Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants.Semantic proximity Read ↗

The papillomavirus E2 proteins.Semantic proximity Read ↗

Separate domains in E1 and E2 proteins serve architectural and productive roles for cooperative DNA binding.Semantic proximity Read ↗

Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functionsSemantic proximity Read ↗

Bovine papillomavirus with a mutation in the E2 serine 301 phosphorylation site replicates at a high copy number.Semantic proximity Read ↗

Sequence-Dependent Interaction of the Human Papillomavirus E2 Protein with the DNA Elements on Its DNA Replication OriginSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.