Article
Cell and molecular biology of gastrointestinal tract cancer.
Current opinion in oncology - 1 Aug 1992
Paraskeva C, Williams A C
Abstract excerpt
The gene for familial adenomatous polyposis coli (APC or FAP), which has previously been linked to chromosome 5q21 has been identified. The APC gene has been found to be altered by point mutations in the germ line of both adenomatous polyposis coli and Gardner's syndrome patients and somatically in tumors from sporadic colorectal cancer patients. During the hunt for the APC gene, the closely linked MCC (mutated...
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