Article
Cell and molecular biology of gastrointestinal tract cancer.
Current opinion in oncology - 1 Aug 1992
Paraskeva C, Williams A C
Abstract excerpt
The gene for familial adenomatous polyposis coli (APC or FAP), which has previously been linked to chromosome 5q21 has been identified. The APC gene has been found to be altered by point mutations in the germ line of both adenomatous polyposis coli and Gardner's syndrome patients and somatically...
Topics
- Adenomatous Polyposis Coli
- Animals
- Biomarkers, Tumor
- Chromosome Aberrations
- Chromosome Deletion
- Colorectal Neoplasms
- Diet
- Gardner Syndrome
- Gastrointestinal Neoplasms
- Genes, Tumor Suppressor
- Genes, p53
- Genetic Predisposition to Disease
- Humans
- Oncogenes
- Rats
- Transforming Growth Factor beta
