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Article

Microheterogeneity of S-glycoprotein of mouse hepatitis virus temperature-sensitive mutants.

Journal of virological methods - 1 Jul 1992

Oleszak E L, Knisley K, Rodkey L S, Leibowitz J L

Abstract excerpt

Mouse hepatitis virus (MHV) strain JHM (MHV-JHM) is a neurotropic coronavirus that causes acute fatal encephalomyelitis in 75-99% of infected mice. The surviving animals may subsequently develop demyelinating disease. We compared the S peplomer protein of the wild type (wt) and five temperature-sensitive (ts) mutants of MHV-JHM. In contrast with the wt, none of these five cause fatal disease (mortality less than...

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Identifiers

PMID: 1322926
DOI: 10.1016/0166-0934(92)90173-b
PMCID: PMC7119594

Genes

SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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