Article
Clustering of discrete cell properties essential for tumorigenicity and metastasis. III. Dissociation of the properties in N-ras-transfected RSV-SR-transformed cells.
International journal of cancer - 30 Jul 1992
Deichman G I, Topol L Z, Kluchareva T E, Matveeva V A, Zakamaldina T A, Uvarova E N, Tatosyan A G
Abstract excerpt
We have previously shown that RSV-SR-transformed hamster cells acquire high resistance to H2O2, i.e. the cytotoxic product of activated macrophages (H2O2R) and that they begin to secrete PGE (PGES), thus inactivating the CTA of NK cells. Among normal cells, the same phenotype is expressed in activated macrophages. In all our RSV-transformed cells these 2 properties were jointly expressed and correlated with high...
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