Article
The fingerprints of the host innate immunity on the cells of primary virus-induced tumors.
Immunology letters - 15 Jan 2001
Deichman G, Dyakova N, Kashkina L, Matveeva V, Uvarova E
Abstract excerpt
As shown earlier, the cells transformed in vitro by various oncogenes, during subsequent in vivo growth were gradually replaced by descendant tumor cells, which co-expressed highly increased H(2)O(2)-catabolizing antioxidant activity (H(2)O(2)(CA)), and the ability to release PGE(2) (PGE(S)) in contact with natural killer cells; v-src was the only oncogene, which in vitro induced cells transformation...
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