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Article

Sequence analysis of the 5' noncoding region of hepatitis C virus.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1992

Bukh J, Purcell R H, Miller R H

Abstract excerpt

We have determined the nucleotide sequence of the 5' noncoding (NC) region of the hepatitis C virus (HCV) genome in 44 isolates from around the world. We have identified several HCV isolates with significantly greater sequence heterogeneity than reported previously within the 5' NC region. The most distantly related isolates were only 90.1% identical. Nucleotide insertions were seen in three isolates. Analysis of...

Topics

Base Sequence
Consensus Sequence
DNA, Viral
Genetic Variation
Hepacivirus
Hepatitis C
Humans
Molecular Sequence Data
Sequence Homology, Nucleic Acid

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1317578
DOI: 10.1073/pnas.89.11.4942
PMCID: PMC49204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1317578-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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