Article
Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes.
Virology - 1 May 1992
Okamoto H, Kurai K, Okada S, Yamamoto K, Lizuka H, Tanaka T, Fukuda S, Tsuda F, Mishiro S
Abstract excerpt
Variable genomic sequences have been reported for RNA cloned from hepatitis C virus (HCV)-infected humans and chimpanzees. We found that four distinct genotypes of HCV could be differentially identified by PCR using type-specific primers. Full-length sequences have so far been reported for three of the four HCV genotypes, and we report herewith the sequence of the fourth type obtained from a Japanese blood donor....
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- Genetic Variation
- Genome, Viral
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Molecular Sequence Data