Article
Sequence analysis of the 5' untranslated region in isolates of at least four genotypes of hepatitis C virus in The Netherlands.
Journal of clinical microbiology - 1 Feb 1994
Kleter G E, van Doorn L J, Brouwer J T, Schalm S W, Heijtink R A, Quint W G
Abstract excerpt
The RNAs of hepatitis C virus (HCV) isolates from 62 patients with chronic HCV infection were analyzed by direct sequencing of the 5' untranslated region. Two important sequence motifs were recognized: one between positions -170 and -155 and the other between positions -132 and -117. These motifs...
Topics
- Adult
- Aged
- Base Sequence
- DNA, Viral
- Genetic Variation
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Middle Aged
- Molecular Sequence Data
- Netherlands
- Polymerase Chain Reaction
- Sequence Homology, Nucleic Acid