Article
Control of segregation of chromosomal DNA by sex factor F in Escherichia coli. Mutants of DNA gyrase subunit A suppress letD (ccdB) product growth inhibition.
Journal of molecular biology - 5 May 1992
Miki T, Park J A, Nagao K, Murayama N, Horiuchi T
Abstract excerpt
The letA (ccdA) and letD (ccdB) genes, located just outside the sequence essential for replication of the F plasmid, apparently contribute to stable maintenance of the plasmid. The letD gene product acts to inhibit partitioning of chromosomal DNA and cell division of the host bacteria, whereas th...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- Chromosomes, Bacterial
- DNA Topoisomerases, Type II
- DNA, Bacterial
- Escherichia coli
- F Factor
- Genes, Bacterial
- Genetic Complementation Test
- Molecular Sequence Data
- Phenotype
- Restriction Mapping
- Temperature