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Article

Expression of the F plasmid ccd toxin-antitoxin system in Escherichia coli cells under nutritional stress.

Canadian journal of microbiology - 1 Jan 2006

Aguirre-Ramírez Marisela, Ramírez-Santos Jesús, Van Melderen Laurence, Gómez-Eichelmann M Carmen

Abstract excerpt

The ccd system of the F plasmid encodes CcdB, a protein toxic to DNA-gyrase, and CcdA, its antitoxin. The function attributed to this system is to contribute to plasmid stability by killing bacteria that lose the plasmid during cell division. However, the function of ccd in resting bacteria is not clear. Results presented show that ccd transcription increases as bacteria enter stationary phase and that the amount...

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PMID: 16541156
DOI: 10.1139/w05-107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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