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Article

Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution.

Journal of virology - 1 May 1992

Martell M, Esteban J I, Quer J, Genescà J, Weiner A, Esteban R, Guardia J, Gómez J

Abstract excerpt

Sequencing of multiple recombinant clones generated from polymerase chain reaction-amplified products demonstrated that the degree of heterogeneity of two well-conserved regions of the hepatitis C virus (HCV) genome within individual plasma samples from a single patient was consistent with a quasispecies structure of HCV genomic RNA. About half of circulating RNA molecules were identical, while the remaining...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1313927
DOI: 10.1128/JVI.66.5.3225-3229.1992
PMCID: PMC241092

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