Article
Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution.
Journal of virology - 1 May 1992
Martell M, Esteban J I, Quer J, Genescà J, Weiner A, Esteban R, Guardia J, Gómez J
Abstract excerpt
Sequencing of multiple recombinant clones generated from polymerase chain reaction-amplified products demonstrated that the degree of heterogeneity of two well-conserved regions of the hepatitis C virus (HCV) genome within individual plasma samples from a single patient was consistent with a quas...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Genetic Variation
- Genome, Viral
- Hepacivirus
- Hepatitis C
- Humans
- Molecular Sequence Data
- Mutagenesis
- RNA, Viral
- Sequence Homology, Nucleic Acid
- Viremia