Inhibition of T cell antigen receptor-dependent phosphorylation of CD4 in human immunodeficiency virus type 1 infected cells.

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Article

Inhibition of T cell antigen receptor-dependent phosphorylation of CD4 in human immunodeficiency virus type 1 infected cells.

The Journal of biological chemistry - 25 Feb 1992

Gaulton G N, Brass L F, Kozbor D, Pletcher C H, Hoxie J A

Abstract excerpt

Inhibitory effects of human immunodeficiency virus (HIV) on T lymphocyte function have been linked to perturbation of signaling through the T cell antigen receptor-CD3 complex. Comparative biochemical analyses of signaling responses were performed in T cells that were either uninfected or chronic...

Topics

Animals
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
CD4 Antigens
Calcium
Cell Line
Cricetinae
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Flow Cytometry
Gene Products, env
HIV Envelope Protein gp120

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HIV Envelope Protein gp160

HIV-1

Humans

Hydrolysis

Phenotype

Phorbol 12,13-Dibutyrate

Source

Open in PubMed

Identifiers

PMID: 1310988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1310988-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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