A temperature-sensitive CHO-K1 cell mutant (tsTM13) defective in chromosome decondensation and spindle deconstruction in M phase.

doi:10.1016/0014-4827(92)90372-f

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Article

A temperature-sensitive CHO-K1 cell mutant (tsTM13) defective in chromosome decondensation and spindle deconstruction in M phase.

Experimental cell research - 1 Feb 1992

Tsuji H, Matsudo Y, Ajiro K, Yasuda H, Hanaoka F, Hayashi A, Utsumi S, Ohba Y, Hori T

Abstract excerpt

A temperature-sensitive CHO-K1 cell mutant, tsTM13, exhibited a delayed cell cycle progression from metaphase to telophase at a nonpermissive temperature and was finally arrested from anaphase to telophase. Metaphase chromosomes were overcondensed and chromosome disjunction in anaphase was uncoordinated. In telophase, sister chromatids were segregated and cytokinesis was completed, but chromosome structure...

Topics

Amino Acid Sequence
Animals
Blotting, Western
CHO Cells
Chromosomes
Cricetinae
Demecolcine
Flow Cytometry
Genetic Complementation Test
Histones
Kinetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitosis

Mitotic Index

Molecular Sequence Data

Mutation

Phosphorylation

Protamine Kinase

Spindle Apparatus

Source

Open in PubMed

Identifiers

PMID: 1309502
DOI: 10.1016/0014-4827(92)90372-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1309502-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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