Article
Deletion of the VP16 open reading frame of herpes simplex virus type 1.
Journal of virology - 1 Jan 1992
Weinheimer S P, Boyd B A, Durham S K, Resnick J L, O'Boyle D R
Abstract excerpt
VP16 (also called Vmw65 and alpha TIF) is a structural protein of herpes simplex virus type 1 (HSV-1) that trans-induces HSV-1 immediate-early gene transcription. This report describes an HSV-1 VP16 deletion mutant that was constructed and propagated in a cell line transformed with a VP16 express...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Blotting, Southern
- Cell Line, Transformed
- DNA Replication
- DNA, Viral
- Immunoblotting
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Open Reading Frames
- Recombination, Genetic
- Simplexvirus
- Trans-Activators
- Vero Cells
- Viral Proteins
- Virus Replication