[Evolution of aneuploidy from diploid colorectal carcinoma as revealed by the analyses of ploidy heterogeneity and Ras mutation patterns].

Article

[Evolution of aneuploidy from diploid colorectal carcinoma as revealed by the analyses of ploidy heterogeneity and Ras mutation patterns].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jun 1995

Sugihara H, Katsura K, Yokoyama K, Hattori T, Fujita S

Abstract excerpt

UNLABELLED: To analyze ploidy alterations during progression of colorectal tumors, we mapped the ploidy constitutions by cytofluorometry using (measurements of metaphase cells in) tissue sections as well as cell suspensions isolated from the tissue sections. Clonality of the tumor with heterogene...

Topics

Aneuploidy
Colorectal Neoplasms
DNA, Neoplasm
Genes, ras
Genetic Heterogeneity
Humans
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.