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Article

[Evolution of aneuploidy from diploid colorectal carcinoma as revealed by the analyses of ploidy heterogeneity and Ras mutation patterns].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jun 1995

Sugihara H, Katsura K, Yokoyama K, Hattori T, Fujita S

Abstract excerpt

UNLABELLED: To analyze ploidy alterations during progression of colorectal tumors, we mapped the ploidy constitutions by cytofluorometry using (measurements of metaphase cells in) tissue sections as well as cell suspensions isolated from the tissue sections. Clonality of the tumor with heterogeneous ploidy constitution was checked by mutation pattern of K-ras codon 12. To assess the significance of polyploidy...

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PMID: 7611777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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